/Deep brain machine interfaces – interacting with human deep brain

Deep brain machine interfaces – interacting with human deep brain

Key idea: Brain-Machine Interface (BMI, also known as Brain-Computer Interface) provides a new dimension for human to interact with machines and the environment. Brain-machine interfaces help restore or improve human physical or mental functions.

Original author and publication date: Science China Press – December 27, 2022

Futurizonte Editor’s Note: Could it be the case that it will be easier for humans to connect with a machine than connecting with other humans?.

From the article:   

The cerebral cortex has long been the research target of brain-machine interface. By recording neural activity in multiple cortical regions to understand human intent, researchers enable paralyzed patients to control robotic arms and prosthetics, and help disabled people communicate effectively.

Conventional brain-computer interfaces allow us to decode sensory and motor signals such as visual responses, hand movements, and speech in constrained lab environment. It is still challenging to apply these technologies to everyday life.

Deep brain regions are heavily involved in basic life functions. It is necessary to investigate deep brain functions to achieve better understanding of how the brain works. Subcortical brain regions are the main targets for invasive neuromodulation and clinical neurotherapy. Structural and functional abnormalities of human deep brain are observed in a variety of neurological and psychiatric disorders, including Parkinson’s disease, Alzheimer’s disease, depression, and obsessive-compulsive disorder, etc. Deep brain machine interfaces focus on understanding and modulating neural activities in deep brain regions. It is an emerging research field with great potential for clinical applications.

The above figure illustrates major methods for recording and stimulation ranging from surface to the deep brain. In addition to recording and decoding, deep brain machine interfaces are also able to modulate pathological states of the brain by delivering therapeutic stimuli. Advanced DBMI technology is designed to record and decode deep neural activity with high spatiotemporal resolution and efficiently configure stimulation parameters for precise modulation of brain states. Developing DBMI with long-term efficacy remains challenging due to our limited understanding of the mechanisms including plasticity and adaptations of the central nervous system.

Since the nervous system mainly transmits information through electrical signals, brain-computer interfaces mediated by electrical signals have attracted the most research interest in this field. The article outlines the current neural electrical activity-based brain-computer interface technologies available for humans and the applications in sensing and modulating brain activity.

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